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It comprises elongated, multinucleated cells called myofibers, which are specialized for contraction [1]

TMAO levels can rise within a few hours post beef consumption and may remain elevated for up to 24 h [12, 31]

The Koeth findings established a biologically plausible mechanism and a population association, but the human cardiovascular evidence on supplemental L-carnitine is mixed some carnitine trials report neutral or even favorable cardiovascular markers, particularly in cardiac and metabolic patient populations

Such efforts hold the potential to advance novel prevention and therapeutic strategies for MASLD

After a further centrifugation (200 x g, 8 min, 20C, Universal 320, Andreas Hettich GmbH, Tuttlingen, Germany), PBMC were resuspended in RPMI medium supplemented with fetal bovine serum, HEPES buffer, L-glutamine, and -mercaptoethanol (all purchased from Biochrom AG, Berlin, Germany)