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It is commonly employed in longevity and age-related signaling models, where researchers examine endpoints such as gene expression patterns, cellular stress responses, and telomere-related pathways in preclinical or in vitro systems

10.1016/j.expneurol.2018.01.003 Exp

How can glutathione deficiency be detected

As mitochondria are theorized to have originated from endosymbiotic purple non-sulfur bacteria, their DNA is reminiscent of bacterial DNA

Also interesting, no nitrosylation of GSH/GSSG was oberved in the presence of iron complexes, which seems to indicate a preferential oxygen activation chemistry by this transition metal ion