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Metformin-induced vitamin B12 deficiency can cause or worsen distal symmetrical, autonomic and cardiac neuropathy in the patient with diabetes

[18] The critical gap is that essentially none of these trials were designed as genotype-stratified, form-versus-form comparisons in the general population the exact design that would be needed to justify genotype-guided form selection

9- McKie AT et al

Additionally, they aid in boosting immunity increasing energy levels serving as a supplement during pregnancy and breastfeeding, addressing absorption issues, post-surgery recovery, and fulfilling the body's vitamin needs

It is indicated for the treatment of fatigue and weakness associated with nutritional deficiencies, as well as in the management of conditions requiring additional vitamin support