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Total spot UV and total skin tone showed continuous improvement in the placebo group until Week 8, but this trend declined at Week 12

Scientifica 2016:5464373

Front Immunol 9:586 Ren K, Jiang T, Zhou HF, Liang Y, Zhao GJ (2018) Apigenin retards atherogenesis by promoting ABCA1-mediated cholesterol efflux and suppressing inflammation

Thus, understanding these mechanisms is crucial for enhancing the delivery of PLGA nanoparticles across the BBB to minimize systemic toxicity Pharmacological drugs loaded PLGA nanoparticles for PD treatment Several studies demonstrated the effectiveness of PLGA nanosystem in encapsulating pharmacological treatments, thereby improving bioavailability, enhancing BBB penetration, and providing sustained drug release