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However, the antitumor efficacy of these low molecular compounds can be limited by their selectivity and non-toxicity without irradiation

Since the synthesis of AA-CoA by ACSL4 is the first step in the incorporation of AA into PLs, the inhibition or overexpression of ACSL4 could modulate the proportion of PL-AA in cell membranes

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Particularly, it increased the gene expression of CYP1A1 , CYP1A2 , CYP2C2 , CYP3A1 , and CYP3A3 , while gene expression of CYP2C23 and CYP2C40 decreased, all in a dose-dependent manner

The liposomal delivery system is a game-changer in how liposomal iron improves absorption, offering a targeted, efficient solution for iron repletion