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Not only was the regulation of the two step glutathione-synthetic pathway unevenly regulated, but the oxidation/reduction cycle of GSH/GSSG was also unbalanced in infested resistant plants

He used it instead as a conceptual model of how genetic components might interact with their surroundings to produce a phenotype

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One MoleculeA Host of Functions An integral modulator of redox homeostasis, neuroprotection, and neuroinflammation, this molecule supports an array of vital biological processes

GSH forms GSSG upon oxidation, which in turn is reduced back by glutathione reductase in an NADPH-dependent mechanism (Couto et al., 2016