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Polycystic Ovarian Syndrome (PCOS) : Women with PCOS have difficulty with ovulation and if you do not ovulate, the follicles never rupture which means that the ovary is left with many small cysts that over time can become very large and painful

On the other hand, under certain conditions such as low availability of substrate or cofactors, endothelial nitric oxide synthase (eNOS) can produce superoxide instead of NO in a condition known as uncoupling

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