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Energy metabolism Helps convert food into energy Causes of Vitamin B12 Deficiency Poor dietary intake (especially vegetarians/vegans) Pernicious Anemia Gastric surgery (loss of intrinsic factor) Malabsorption disorders Long-term use of some medications (e.g., metformin) Signs and Symptoms of Deficiency Fatigue and weakness Pale skin Shortness of breath Numbness or tingling in hands and feet Difficulty walking Memory problems or confusion Smooth, red tongue (glossitis) Complications Megaloblastic Anemia Peripheral Neuropathy Cognitive impairment if untreated Diagnosis Blood test for serum Vitamin B12 level Complete blood count (shows macrocytic anemia) Elevated homocysteine or methylmalonic acid Treatment Vitamin B12 supplements Vitamin B12 injections for severe deficiency or malabsorption Dietary improvement Vitamin B12 deficiency can cause both anemia and nerve damage, so early diagnosis and treatment are important

For Group 2 DEGs (WT-unique genes), the analysis did not identify any specific pathways

Conversely, medications that improve gastrointestinal health might enhance vitamin retention and prolong its effects

If you cancel the application If you interrupt the treatment, you endanger the success of the treatment

It is currently available primarily through compounding pharmacies for research purposes or as prescribed by a licensed practitioner under specific state regulations governing compounded medications