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In this trial, the patients studied at 13 years post diagnosis were likely to have lost the majority of nigral and striatal dopaminergic function 56

Notably, the subgroup analysis demonstrated that individuals with a BMI of less than 35 35 kg/m 2 or an age of less than 55 years exhibited heightened sensitivity to elevated selenium levels compared with those with a higher BMI or older age, when serum selenium concentrations exceeded the saturation threshold of 2.56 M (approximately 201.6 g/L)

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