glutathione glucuronidation reaction (a) and preferred chemical structures for Phase II consists of covalent
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial General Principles of Pharmacology: Drug Metabolism glucorindation vs glutathione Confident characterization and identification of glucuronide metabolites using diagnostic fragments from electron activated dissociation (EAD) Glucuronidation an overview Phase II Reactions Biotransformation of Drugs Mechanism of the glucuronidation reaction catalyzed by Download Scientific Diagram
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