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This conversion process can be less efficient, especially in individuals with certain health conditions or genetic variations

The absence of IGF-1 elevation and glucose metabolism impairment represents a significant safety advantage for long-term applications

Ye Q, Xu G, Huang H, Pang S, Xie B, Feng B, Liang P, Qin Y, Li S, Luo Y, Xue C, Li W (2023) Nicotinamide N -Methyl Transferase as a Predictive Marker of Tubular Fibrosis in CKD