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In the case of hysterectomy, pretreatment with GnRHA reduced duration of surgery (9.59 minutes, 95% CI 15.9 to 3.28) and of blood loss (MD 25 mL to 148 mL), led to a lower utilization of blood transfusions (OR 0.54, 95% CI 0.3 to 1.0), and fewer postoperative complications (OR 0.54, 95% CI 0.3 to 0.9)

10.1021/bi300954g 21 BrownC

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Chronic psychoemotional stress, sustained hypothalamicpituitaryadrenal activation, andunder some conditionsdistress-related dysregulation promote latent IR and correlate with cardiovascular complications [838,1130,1131,1132,1133]