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In addition to this function, GPX4 regulates the mitogen-activated protein kinase/nuclear factor kappa-light-chain-enhancer of activated B cells (MAPK/NF-B) signal axis to prevent ECM degradation (Miao et al., 2022

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J Neurosci 33(49):1908619098

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In mice, cisplatin damaged myelinated fibers of the sciatic nerve, diminished the action potential amplitude and reduced the nerve conduction velocity of the caudal sensory nerve (Boehmerle et al., 1994

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There are some newer treatments that offer the potential to reverse the wear-and-tear in your joint and actually help your body rebuild the damaged cartilage

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