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Previous findings indicated that GPx1 is downregulated in PDA tissues, which may be correlated with malignant biological behavior in PDA 43,44

However, other studies have shown that frequency of hypoglycemic events does not increase with rhIGF-1 therapy, and effective prevention of glycemic decline can be maintained through proper nutrition and monitoring [62,63,64]

Treatment with the ferroptosis inhibitor Lip-1 significantly reduces renal iron and MDA levels, attenuating fibrosis and dysfunction (189)

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