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Blood 105 , 46134619 (2005)

The STAT3 signaling pathway primarily contributes to immune suppression and is typically stimulated by cytokines such as interleukin-6 (IL-6), IL-10, and certain growth factors, including epidermal growth factor (EGF), transforming growth factor- (TGF-), and insulin-like growth factor (IGF) (309, 310)

Its then sieved and transferred to a washing pond, before being hand-washed over a mesh-screen, ensuring that only pure spirulina is processed

Infliximab was able to deplete the signal from the recombinant TNF spiked sample but had no impact on the assay signal in any of the clinical samples, indicating that the antibody assay was measuring bona fide anti-AMG 966 antibodies ( Figure 7C )