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Under the conditions of unilateral ureteral obstruction and renal ischemia/reperfusion injury, tubular necroptosis is markedly upregulated, which in turn promotes NOD-like receptor protein 3 (NLRP3) inflammasome activation leading to renal fibrosis

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The synthesized nanoceria was spherical and possessed an average size of 7.0 0.2 nm and 5.0 0.2 when the sample had been discharged with plasma for 15 min and 25 min respectively

Gao S-F, Qi X-R, Zhao J, Balesar R, Bao A-M, Swaab DF