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Hepatic APAP metabolism results in the production of the reactive metabolite N -acetyl- p -benzoquinone imine (NAPQI), which under physiological conditions is cleared by its conjugation with glutathione (GSH) to prevent its targeting to mitochondria

Source : Mandal, P

Clean tubing as soon as possible after feeding to prevent milk drying inside

While body weight provides general guidance, individual response patterns matter more than strict weight-based calculations