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The reviewer FH declared a shared affiliation with several of the authors, EG-B, VV-V, EA, and SM-R, to the handling editor at the time of review

We tested whether, and to what degree, each metabolite mediated the association between a risk factor and T2D risk using the CMAverse R package 120 , adjusting age, sex, smoking, BMI and PA (if not the tested risk factor), calorie intake and other cohort-specific covariates, separately in NHS/HPFS, SOL and WHI

Every batch is tested to ensure it meets the highest safety and purity standards

Supports Healthy Aging: A review of several studies conclude that supplementing high dose vitamin C results in increased skin elasticity, better color, and reductions in facial wrinkling/roughness/pore size

Churchward-Venne TA, Burd NA, Mitchell CJ, West DW, Philp A, Marcotte GR, et al