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Overall, the application of COMT inhibitors requires balancing the clinical benefit of extended "on" time against the risk of exacerbating dyskinesia

Nat Neurosci 25:11341148

Subsequently, 1 mg ml 1 (288 U ml 1 ) collagenase solution was added to give a final collagenase concentration of 5 U ml 1 (17 g ml 1 )

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