amino acid precursors to glutathione Newly revealed function could be used boost antioxidant levels Glutathione - PMC

Microglia are transformed into DAM by recognizing Neurodegeneration-Associated Molecular Pattern (NAMP) danger signals which leak from damaged neuronal cells in analogy to the peripheral immune systems pathogen- and damage-associated stress signals (PAMPs and DAMPs) 23

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Importantly, MS patients who showed a significant increase in the expression of NRF2s downstream target, NQO-1, following DMF treatment were more likely to achieve no evidence of disease activity after 1 year (Hammer et al., 2018)

L., Nambisan, B., & Helen, A

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