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Vitamin B12 is also associated with fat and carbohydrate metabolism and protein synthesis

Mol Med Rep 12:11511156 Zou J, Zhu L, Jiang X, Wang Y, Wang Y, Wang X, Chen B (2018) Curcumin increases breast cancer cell sensitivity to cisplatin by decreasing FEN1 expression

R., Marston, W

10.1111/j.1475-6773.2012.01435.x 28

These findings suggest that MPLA reprograms macrophage antimicrobial function through alternative, NO-independent mechanisms, likely dominated by ROS-mediated oxidative stress and metabolic reprogramming, rather than canonial nitrogen-centered cytotoxic pathways