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Signs of infection (increasing redness, warmth, swelling, or pus) require immediate discontinuation and medical evaluation

It really comes down to your goals, comfort level, and lifestyle

The viscosity also increases, but the curve is flatter and peaks around 70 mPas before declining slightly, suggesting that the preservative interferes with network formation and reduces the strength of the gel

The Ordinary Soothing & Barrier Support Serum: (More details in this article: Focus on: ceramides) The famous pink The Ordinary serum

But for a 100mg vial that will likely be used over a few weeks or months, refrigeration is the far safer and more practical approach