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This paradox is critical for appreciating the metabolic modification of tumor cells, as a high mTOR activity can increase survival by inhibiting the autophagy pathway, permitting an accumulation of the necessary proteins for fast cell progression and proliferation (108)

Med 13 , 42294238 (2009)

El-Yazied, H.G

Associate Professor, Universidade Fernando Pessoa Besides being the most important building blocks of proteins aminoacids can also be used as precursors of nitrogen-containing molecules : hemes, nucleotides, glutathione, physiologically-active amines, etc

(1) Immune checkpoint inhibitor therapy, by blocking immune checkpoint molecules, reactivating the anti-tumor activity of T cells, and thereby enhancing the immune systems attack on tumor cells [243]