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Few studies in animals have shown a clear mechanistic link between MGO and AGEs and the pathological effects it has on the brain

[DOI] [PMC free article] [PubMed] [Google Scholar] 169.Kruman I.I., Mouton P.R., Emokpae R., Jr., Cutler R.G., Mattson M.P

Squadrone, S

Dbrowski Coordination Chemistry Reviews.2020

To advance clinical application, future research should develop multimodal biomarker panels by integrating technologies such as mass spectrometry imaging, spatial transcriptomics, and single-cell lipidomics, combined with artificial intelligence to define a distinct ferroptosis signature in neurodegeneration