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For instance, sodium butyrate intake was reported to reduce PD-related motor symptoms via mechanisms associated with gut microbial dysbiosis regulation 43 , intestinal barrier protection through the activation of G-protein-coupled receptor 109 A (GPR109A) 44 , and stimulation of glucagon-like peptide-1 45

However, patients enrolled in most related studies reported painful DPN resulting in sleep problems and more severe pain leading to worse sleep quality [11, 32]

Selenium depletion affects the biosynthesis of GPX4 and subsequent antioxidative activity [48]

Low-Glycemic Choices: High blood sugar fuels inflammation and dysbiosis

Sometimes, its as simple as diet