foxo4-dri senolytic mouse 2023 2024 Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging: Cell Peptide targeting senescent cells restores – FOXO4-DRI regulates endothelial cell senescence
FOXO4 DRI regulates endothelial cell senescence via the P53 signaling pathway PMC The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications CHK2 USP37 axis stabilizes FOXO4 to sustain senescence and evade apoptosis PNAS Senolytics: from pharmacological inhibitors to immunotherapies, a promising future for patients' treatment npj Aging FOXO4 DRI: Human Trial Status, Cancer Research & Senolytic Data
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