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Recent findings intriguingly suggest that OPTN plays a role in the senescence of renal tubular epithelial cells when exposed to elevated glucose levels (Xiao et al., 2017)

Higher relative abundance of proinflammatory bacteria like Eggerthella, Atopobium was found to be increased, and decreased relative abundance of Faecalibacterium in the subjects with MDD (Knudsen et al., 2021)