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For antioxidant enzymes and MDA analyses, tissue samples were rinsed in PBS and minced and homogenized in PBS with a glass homogenizer on ice, then thawed at 28C and centrifuged at 20003000 rpm for 20 min

7.2 Complex cellular infiltration and angiogenesis Tophi, the defining pathological structures of chronic gout, arise through the coordinated actions of complex immune cell infiltration, persistent inflammation, and pathological angiogenesis rather than MSU crystal deposition alone

Healing wounds

(C) MCF7- V5_GSTP1 and -GSTP1_V5 cells were metabolically labelled with -alkynyl-palmitate for 24 h ( Top panel )

However, we view these regulatory changes as an opportunity to refine our approach and ensure that all treatments we offer meet the highest standards of medical evidence