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Description

10.1002/bit.23022 158

As summarized by Stier, Vos, and Kenley in 2013, the pre-specified primary endpoint for statistically significant weight change across the dose range and study duration was not met, while the compound's tolerability profile remained comparable to placebo

IGF-1 is a small peptide that circulates in plasma with the majority (98%) bound to the IGF-binding proteins (IGFBP)

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