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These findings suggest that the upregulated expression of adipogenic, lipid synthesis, and storage-related genes in the 50W group increases phosphatidylcholine content and reduces acylcarnitine levels in muscle tissues

Cardiovascular disease accounts for approximately 50% of deaths in the ESRD population, and complications of left ventricular dysfunction and left ventricular hypertrophy lead to considerable morbidity

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Recently, the protective role of the mitochondrial unfolded protein response (UPR mt ) in cardiac pathophysiology has drawn increasing attention