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Several studies in patients with psoriasis and psoriatic arthritis have observed an increased abundance of Firmicutes in the gut microbiota (162)

These factors notwithstanding, the problem of DILI attributable to HDS remains an important concern for Americans, as HDS are the second most common cause of DILI among enrollees into the DILIN

The optimal dosing regimens and duration of supplementation are also important aspects to be further explored regarding the risk versus curative benefits