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DISCUSSION The goal of this study was to develop an AnglV-derived molecule that retained the pro-cognitive/anti-dementia activity of AnglV and Nle'-AnglV but possessed improved pharmacokinetic properties, thus allowing it to penetrate the BBB in sufficient quantities to reach therapeutic levels in the brain

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[8]Beretta GArtali RRegazzoni LPanigati MFacino M.Glycyl-histidyl-lysine (GHK) adalah peredam abjad-4-hy-droxy-trans-2-nonenal perbandingan dengan carnosineinsightdalam mekanisme reaksi dengan elektrosprayionisasi spesifikasi massa trometry1H NMR,dan teknik komputasiChem Res Toxi-col.2007 Sep;20(9):1309-14 [9]BerettaGarlandiniEARtaliRAntonJMMaffei FacinoR Acrolein kemampuan sekuestrasi tripeptida endogen glikil-histidil-lisin(GHK): karakterisasi produk konjugasi oleh ESI-MSn dan perhitungan teoretis Pharm Biomed Anal 2008 Jul15;47(3):596-602

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