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R_4-hydroxycholesterol decreased by 20% under itraconazole and increased by 48% under fluconazole treatment

It shows the controlled drug release based on the initial burst release obeys a controlled diffusion mechanism [31]

That's not on you

Understanding metabolic perturbations in antibiotic resistance provides crucial insights into bacterial adaptations of their metabolic networks to survive and persist under antibiotic stress, potentially unveiling novel therapeutic targets