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Moreover, in contrast to protein oxidation, lipid peroxidation, and cell death following A40 or A42 addition to neuronal cultures, none of these occurred with the norleucine-substituted A peptide (112114), i.e., the Met35 residue of A42 was hinted at as being important in the free radical associated with this neurotoxic peptide

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Drug entrapment efficiency A total of 100 mg of beads was shaken in phosphate-buffered saline (100 mL, PBS) at 100 rpm for 24 h