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IGF-1 LR3 (Insulin-like Growth Factor 1 Long Arg3) is a synthetic variant of human IGF-1 , modified to increase both its potency and half-life

doi: 10.3390/cancers13050986 109 OhtaASitkovskyM

In vivo photothermal and antitumor experiments confirmed that the material can generate large amounts of heat and ROS, leading to apoptosis and tumor-growth restriction