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A follow-up trial in 2010 confirmed the 0.5mg dose as the optimal balance between efficacy and tolerability, producing 9.2% mean reduction with lower cardiovascular stimulation

Balakrishnan B, Mohanty M, Pr U, Athipettah J (2005) Evaluation of an in situ forming hydrogel wound dressing based on oxidized alginate and gelatin evaluation of an in situ forming hydrogel wound dressing based on oxidized alginate and gelatin

At 1 h after administration, [ 3 H]proline accounted for 86.65% of the plasma radioactive components

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First, amylin receptor activation in the area postrema (AP) directly stimulates nausea centres in the brainstem