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doi: 10.1038/mp.2016.213 88 WangJ.HuangH.LiuC.ZhangY.WangW.ZouZ.et al

The interaction between CXCL12, a chemokine secreted by CAFs and epithelial BC cells, and its receptor CXCR4 on MDA-MB-231 breast cancer cells promotes the penetration by MDA-MB-231 cells of a monolayer of human brain microvascular endothelial cells (HBMECs), as well as increasing the permeability of these cells