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This section explores how these approaches enhance the efficacy of AIM and thereby accelerate progress toward a functional cure

PMID: 28578301

Its surface is characterized by a predominantly positive charge at the inward entrance and a hydrophobic profile at the cavity apex (Fig

Interestingly, GSTO1 was identified as one of the potential cellular targets of piperlongumine, an electrophilic compound exerting selective cytotoxicity against cancer cells through an oxidative cell death mechanism (Supplementary Table 25) 37