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Anandamide, on the other hand, prevented the development of breast and prostate cancer cell lines when the levels of prolactin and nerve growth factor receptors were decreased (55)

Critically, impaired mitochondrial energetics are an early pathogenic event in Smyd1 -KO hearts preceding structural remodeling, which is correlated with significantly reduced expression of the key metabolic regulators PGC-1, PPAR, and retinoid X receptor alpha (RXR)

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Compared with the control samples, Pb treatment increased MDA and H 2 O 2 values by 61 and 53%, respectively, indicative of oxidative burst