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doi:10.1038/s41598-017-09823-9

Previously, we showed that amino acids 371-386 of LMP1 are sufficient to induce TRAF6-dependent CTAR2 signalling 31

However, human neurogenesis studies directly measuring these effects and linking them to cognitive outcomes remain absent, limiting current translation to clinical neurodegenerative disease prevention [15]

DSIP freely crosses the blood-brain barrier and is readily absorbed from the gut without being denatured by enzymes

It's currently in use for this indication in several countries, including Canada, under the brand name Lutrelef, which is administered via the LutrePulse pump injector device [3]