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Feb 2010;6(2):153-170

As noted by Mahiques-Santos, the higher incidence of side effects associated with MT-II is due to its being less receptor-specific than MT-I [1]

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Iron is a vital trace element for the maintenance of normal cellular physiology, plays a role in producing deoxyribonucleic acid (DNA) and adenosine triphosphate(ATP), joins in the tricarboxylic acid (TCA) cycle, functions as cofactor for various proteins in the electron transport chain, and is implicated in the synthesis of myelin phospholipids and multiple neurotransmitters in the central nervous system (CNS) (Ke and Qian, 2007