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In macrophages, different Clostridium derivatives exert multifarious effects: CB -derived EVs inhibit the MAPK/NF-B pathway through the miR-199a-3p-map3k4 axis, inducing M2 polarization (8486)

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The 8 SNPs showed no association with smoking behavior in an independent dataset of 74,035 participants, ruling out smoking as a confounding pathway through the genetic instrument