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Furthermore, -KG, a derivative of glutamine metabolism, binds to oxoglutarate receptor 1 (OXGR1) on macrophages, triggering MAPK signaling and suppressing MHC-II antigen presentation, thereby promoting immune evasion and tumor progression [168]

Effects of Nicotinamide N-Methyltransferase on PANC-1 Cells Proliferation, Metastatic Potential and Survival Under Metabolic Stress

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