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Integrative and functional medicine practices incorporate B-12 therapy into broader nutrient optimization protocols

Deficiency is common in those with fatigue, brain fog, or nutrient absorption issues, especially individuals with gastrointestinal conditions, vegans and vegetarians, or those taking medications like metformin or proton-pump inhibitors

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In some embodiments, the invention encompasses a method of providing muscular therapy by administering a cation of Formula I, wherein: R 1 is C 1-4 alkyl