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About this article Cite this article Lin, YS., Thayer, K.A., White, P

(3) dynamic changes, particularly in glutathione, in re- sponse to increased intracellular ROS

If, for example, this is a new HIV drug and the best treatment already includes 3 active drugs, then it could be difficult to see any difference between the new drug and the placebo, because both groups will already do very well