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Description

The mechanism is scientifically sound and consistently supported by animal data, but human efficacy and safety have not been established through clinical trials

doi: 10.1182/blood.V118.21.3618.3618 131 EstanMCCalvinoECalvoSGuillen-GuioBBoyano-Adanez MdelCde BlasEet al

doi: 10.1002/pmic.201800486 32 XiaoSJin-XiangYLongTXiu-RongLHongGJie-ChengYet al

COQ4 mutations cause a broad spectrum of mitochondrial disorders associated with CoQ10 deficiency

The sdf file of the 3D structure of HT was converted to mol2 format using Open Babel software and then converted to PDBQT format using AutoDock 1.5.7 software