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These combined mechanisms can improve fat metabolism, reduce inflammation, and preserve lean muscle during fat loss

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Activation of the kynurenine pathways is often associated with reduced free circulating (reviewed by Hazrati et al., 2024) and brain tryptophan levels (Hazrati et al., 2024

Not approved for human use, not for therapeutic applications, and not for in vivo studies in humans

The expert panel proposes measures to address this underdiagnosed burden, highlighting the importance of early intervention through innovative screening methods, integrated care approaches, and therapeutic strategies