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Cellular cisplatin accumulation is mainly determined by copper transporter-1, responsible for cisplatin uptake 6,7 and ABCB1 , encoding multidrug-resistant protein 1 (MDR1) involved in increasing platinum-drug export 8,9

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This is relevant, as platelets are the first cells that arrive at a site of injury to release various factors that initiate the repair process

It is derived from the C-terminal end of alpha-melanocyte-stimulating hormone, and it retains the parent molecule anti-inflammatory properties without the melanogenic (skin-darkening) effects