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Small extracellular vesicles encompass bioactive molecules that, when administered in a POF mouse model or cocultured with GCs from POF patients, facilitate ovarian recovery by increasing follicle numbers at all developmental stages (primordial, primary, secondary, and antral) and normalizing hormone levels, including E2, AMH, and FSH

In higher eukaryotes, phosphorylation, acetylation, and ubiquitination are usually ROS-sensitive PTMs (Liu et al., 2013

This approach appears to optimize results for targeted injury treatment

For in vitro research only

Carmeli E, Coleman R, Reznick AZ: The biochemistry of aging muscle