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2022;146 doi: 10.1016/j.biopha.2021.112560

For non-macrophage tropic respiratory viruses such as RSV and measles, non-neutralizing antibodies have been shown to induce ADE and ERD by forming immune complexes that deposit into airway tissues and activate cytokine and complement pathways, resulting in inflammation, airway obstruction and, in severe cases, leading to acute respiratory distress syndrome 10,11,22,23

Every time you puncture that stopper with a needle, you create a tiny channel that can allow air to enter the vial

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